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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INCENP
All Species:
10.61
Human Site:
S421
Identified Species:
25.93
UniProt:
Q9NQS7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQS7
NP_001035784.1
918
105429
S421
N
P
K
P
A
A
S
S
P
E
T
P
S
A
G
Chimpanzee
Pan troglodytes
XP_001151716
913
104783
S421
N
P
K
P
A
A
S
S
P
E
T
P
S
A
G
Rhesus Macaque
Macaca mulatta
XP_001118481
897
102420
S420
N
P
K
P
A
A
S
S
P
E
T
P
S
A
G
Dog
Lupus familis
XP_853705
896
101812
G418
G
S
R
P
L
A
G
G
Q
E
T
P
S
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU62
880
101190
A396
P
T
S
K
P
A
A
A
G
Q
T
T
T
V
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519483
997
113500
P494
N
K
I
A
I
G
T
P
E
A
R
L
E
A
N
Chicken
Gallus gallus
P53352
877
100922
A597
K
I
K
K
R
A
A
A
K
K
M
E
E
A
E
Frog
Xenopus laevis
O13024
873
101180
R507
R
Q
R
L
D
A
L
R
K
K
E
E
A
E
L
Zebra Danio
Brachydanio rerio
XP_002666634
833
95304
S457
D
V
K
L
G
S
G
S
V
E
R
E
R
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMA7
1430
159034
R741
H
R
I
L
Y
P
G
R
P
E
V
P
P
S
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
92.9
79.4
N.A.
72.3
N.A.
N.A.
47.3
46.6
47
30.1
N.A.
20.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
94.7
85.4
N.A.
82
N.A.
N.A.
62.7
63.5
63.7
49.2
N.A.
36.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
46.6
N.A.
13.3
N.A.
N.A.
13.3
20
6.6
20
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
40
N.A.
N.A.
20
40
26.6
33.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
30
70
20
20
0
10
0
0
10
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
60
10
30
20
20
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
10
30
10
10
0
0
0
0
0
40
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
20
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
50
20
0
0
0
0
20
20
0
0
0
0
10
% K
% Leu:
0
0
0
30
10
0
10
0
0
0
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
10
30
0
40
10
10
0
10
40
0
0
50
10
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
10
0
0
0
10
10
% Q
% Arg:
10
10
20
0
10
0
0
20
0
0
20
0
10
0
0
% R
% Ser:
0
10
10
0
0
10
30
40
0
0
0
0
40
10
0
% S
% Thr:
0
10
0
0
0
0
10
0
0
0
50
10
10
0
0
% T
% Val:
0
10
0
0
0
0
0
0
10
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _